The simple monosubstituted guanidines of mammalian brain
نویسندگان
چکیده
منابع مشابه
The occurrence of guanidinoacetic acid and other substituted guanidines in mammalian liver.
Lardy, H. A. & Adler, J. (1956). J. biol. Chem. 219, 933. Long, C. (1952). Biochem. J. 50, 407. McAnnally, R. A. & Phillipson, A. T. (1942). J. Physiol. 101, 14. McKenzie, H. A. & Wallace, H. S. (1954). Aust. J. Chem. 7, 55. Pennington, R. J. (1952). Biochem. J. 51, 251. Pennington, R. J. (1954). Biochem. J. 56, 410. Pennington, R. J. & Sutherland, T. M. (1954). Biochem. J. 58, vii. Pennington,...
متن کاملNω-nitro-nω'-substituted Guanidines: a Simple Class of Nitric Oxide Synthase Inhibitors.
A series of Nω-nitro-Nω'-substituted guanidines has been prepared as potential inhibitors of the human Nitric Oxide Synthase (NOS) isoforms. The reported utility of aminoguanidine and nitroarginine in iNOS inhibition points to a potential similar utility for analogs of nitro-guanidine. The compound library was tested against the three isoforms of Nitric Oxide Synthase (eNOS, iNOS and nNOS). Sev...
متن کاملFirst iron-catalyzed guanylation of amines: a simple and highly efficient protocol to guanidines
The first iron-catalyzed guanylation of amines is reported. Commercially available Fe(OAc)2 acts as an excellent catalyst for the addition of amines to carbodiimides. The reaction is broadly applicable to a variety of primary, secondary, and heterocyclic amines, and tolerates a wide range of functionalities allowing the easy preparation of a large family of guanidines. The low price and low tox...
متن کاملBicyclic-guanidines, -guanidinates and -guanidinium salts: wide ranging applications from a simple family of molecules.
Bicyclic guanidines have physical, electronic and chemical properties that differentiate them from their acyclic counterparts, with many of these characteristics directly imposed by the rigid framework. These distinctive features have led to this class of molecule finding practical applications in many areas of chemistry, including organocatalysis and as ligands in coordination compounds. In ad...
متن کاملMechanochemical synthesis of thioureas, ureas and guanidines
In this review, the recent progress in the synthesis of ureas, thioureas and guanidines by solid-state mechanochemical ball milling is highlighted. While the literature is abundant on their preparation in conventional solution environment, it was not until the advent of solvent-free manual grinding using a mortar and pestle and automated ball milling that new synthetic opportunities have opened...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1960
ISSN: 0306-3283
DOI: 10.1042/bj0770484